The CD95 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ALPS1A, APO1, CD178, CD95, CD95L, Fas, fas ligand, Fas receptor, Fasl, FASN, TNFR6, and YWHAZ. This antibody recognizes Human, Mouse, and Rat antigen. The CD95 antibody has been validated for the following applications: Western Blot.
Description
Rabbit polyclonal CD95 antibody
Fas/Apo-1/CD95 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a member of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis in Fas expressing cells. Both Fas and TNF-R contain the 70 amino acids cytoplasmic "death domain" that is responsible for transmitting signal for apoptosis